A DIAGNOSTICALLY CHALLENGING CASE OF FEBRILE ULCERONECROTIC MUCHA-HABERMANN DISEASE IN AN ADULT FEMALE SUCCESSFULLY TREATED WITH METHOTREXATE AND CYCLOSPORINE

Febrile ulceronecrotic Mucha-Habermann disease (FUMHD) is a rare and severe variant of pityriasis lichenoides et varioliformis acuta (PLEVA) characterized by intermittent pyrexia, acute onset of generalized ulceronecrotic lesions, and histopathology suggestive of PLEVA.Prompt diagnosis and treatment are necessary to halt the progression of this pot

Background: Nitric oxide synthase 1 adaptor protein (NOS1AP; previously named CAPON) is linked to the glutamatergic postsynaptic density through interaction with neuronal nitric oxide synthase (nNOS).NOS1AP and its interaction with nNOS have been associated with several mental disorders.Despite the high levels of NOS1AP expression in the hippocampu

Exploring the spatial non-stationarity and driving mechanisms of trade-offs/synergies among land use functions(LUFs), which are crucial for effectively alleviating human-land conflicts and enhancing the overall benefits and sustainable development of regional territorial space.While most existing studies have analyzed the spatio-temporal patterns a

The handicraft industry remained an integral part of the mixed economy of the Russian Empire.Foreign artisans, primarily those of German descent, played a significant role in the capital cities from the 18th century onward.Most of these craftsmen relocated to Russia in response to an invitation from the Tsarist government.Around the turn of the 18t